After a 2024 rebuff, AstraZeneca and Daiichi Sankyo’s star antibody drug conjugate Enhertu has been deemed cost effective for NHS use in HER2-low advanced breast cancer by England and Wales' drug value assessor.
Exclusive: Ten category C prisons in England and Wales asked to add second beds, which will breach safe occupancy limits The Prison Service has drawn up plans to “double up” hundreds of prisoners in temporary prefabricated cells built for one person, at the request of the Ministry of Justice, leaked documents show. Amid an ongoing overcrowding crisis in England and Wales, governors of 10 category C prisons have been asked to sign off the installation of second beds in “rapid deployment cells [RDCs]”. Continue reading...
The Guardian•Rajeev Syal Home affairs editor16 Sept
The number of shoplifting offences recorded in England and Wales in 2025-26 is still above pre-pandemic levels.
BBC16 Sept
Keira Bevan is to switch half-back roles after being selected to play at 10 for Wales' WXV opener against South Africa in Cardiff on Friday.
BBC16 Sept
In today’s newsletter: It is hard to tell fact from fiction when it comes to AI. What is really going on – and what should the government do about it? Good morning. As a general rule, it pays to be suspicious of any gigantic company that claims it’s developing a tool capable of destroying humanity. But in recent days, a number of warnings from the AI industry have suggested that even tech insiders are starting to worry about what they have unleashed. In a lofty essay published on Saturday, Dario Amodei, the founder of Anthropic (the company behind Claude), argued that tech companies need to “slow” the pace at which they’re developing the newest and most sophisticated AI models. Lucy Letby | Three babies might have survived if hospital had acted upon concerns over Lucy Letby, an inquiry has found . Lady Justice Thirlwall condemned the ‘complete failure’ to protect babies on neonatal unit at Countess of Chester hospital. UK politics | The leader of Reform UK in Wales stood down after arrest on suspicion of assault . Dan Thomas, a former Tory councillor, was elected to Senedd as leader of the opposition in May. AI | The progressive senator Bernie Sanders and rightwing strategist Steve Bannon have called for restrictions on artificial intelligence (AI) but offered competing visions for what they termed a “cold war” with China. UK news | Young people in Rotherham face a local jobs market with the fewest suitable opportunities in Britain, according to a report that warns stark regional divisions are fuelling a crisis in youth work. Defence | John Healey is in talks with the Canadian government about joining a new global defence bank intended to help allies rearm to counter mounting security threats, just weeks after Rachel Reeves rejected the move. Continue reading...
The Guardian•Hettie O'Brien16 Sept
After a "sleepless night", Wales boss Craig Bellamy decided to turn down the chance to manage Burnley - but has it affected what fans think of him?
BBC16 Sept
Actor, who made history at the Emmys, thanked the ‘great and the good people of Wales’ for nurturing his talent When Matthew Rhys made history as the first actor ever to win two best lead Emmy awards in one night, he paid tribute to his roots. “To the great and good people of Wales, who were as much a nurturer as anyone else,” said the proud Welshman now living in New York, “We are a small but mighty nation”. “Diolch yn fawr iawn,” he added, meaning “thank you very much” in Welsh. Continue reading...
The Guardian•Caroline Davies15 Sept
Dan Thomas, a former Tory councillor, was elected to Senedd as leader of the opposition in May The leader of Reform UK in Wales is standing down after he was arrested and bailed on suspicion of assault. Dan Thomas, a former Tory councillor, was announced as Reform UK’s Welsh leader by Nigel Farage in February. He was elected to the Senedd as leader of the opposition in May’s election. Continue reading...
The Guardian•Ben Quinn and Bethan McKernan15 Sept
She has played rugby for Wales, is putting a Welsh spin on Princess Leia and is returning to TV screens as Shirley, the explosive, traumatised MI5 agent. Why is Edwards so drawn to liars, crooks and sneaks? There was a moment, just before Aimee-Ffion Edwards jumped off a nightclub balcony in Slow Horses, when she had to lie to herself about what she was about to do. “It was quite hard,” says the actor. “You basically tell yourself, ‘You’re not jumping.’ Obviously, you know you’re harnessed in, but you’re also going, ‘This is mad! This is mad! This is mad!’” She laughs. “I couldn’t feel my fingers for a second. I was like, ‘Huwwaah!’” She sucks in her breath, then says: “But there were 200 people stood there watching. You’re like, ‘Well, I gotta do it.’” Continue reading...
The Guardian•Donna Ferguson15 Sept
Wales have been dealt another injury blow ahead of their WXV Global Series with Kayleigh Powell ruled out of the entire campaign.
BBC15 Sept
‘I’ve never done anything for money,’ Bellamy says He was in intensive care last year after appendix rupture Craig Bellamy said he rejected the chance to take charge of Burnley in the summer after deciding the Wales job is “the right place for me”. The 47-year-old was among the managers targeted by the Championship club, who appointed Nicky Hayen. Bellamy is preparing to lead Wales in the Nations League, with next Thursday’s trip to Portugal the first of four matches across the extended international break. Bellamy spent two years on the staff at Burnley, working as an assistant to Vincent Kompany and taking caretaker charge after Kompany left for Bayern Munich. Burnley were granted permission to hold talks with him after a triggering release clause in his Wales contract. Continue reading...
The Guardian•Ben Fisher15 Sept
Craig Bellamy says he was "comfortable" turning down the chance to return to club football and reiterated his desire to continue with Wales.
BBC15 SeptCraig Bellamy says he was "comfortable" turning down the chance to return to club football and reiterated his desire to continue with Wales.
BBC15 Sept
The first ministers of three of the four nations making up the UK have met in Wales to discuss plans to move for independence from the Kingdom.
The Sydney Morning Herald15 Sept
Sky Sports15 Sept
The Red Roses captain says nobody should have to choose between their career and having a family The introduction of funding for egg freezing and wider fertility treatment in women’s football has started a wider discussion about fertility in women’s sport with the Red Roses captain, Meg Jones, shining a light on the topic in rugby. The Spanish football federation and Chelsea have both announced financial support around fertility recently and Jones has said it is something the Red Roses should “jump on too”. On the Good, the Scaz and the Rugby podcast, Jones described those decisions made in football as “class” before revealing that she and her fiancee, former Trailfinders and sevens star Celia Quansah, have been to get their egg count checked. The admission prompted her England teammate Hannah Botterman to share that she and her partner, the Wales player Georgia Evans, had also been researching their IVF journey. Continue reading...
The Guardian•Sarah Rendell15 Sept
Craig Bellamy hands a first call-up to Cardiff City forward Cian Ashford for Wales' Nations League A campaign but is without key defender Joe Rodon.
BBC15 SeptCraig Bellamy hands a first call-up to Cardiff City forward Cian Ashford for Wales' Nations League A campaign but is without key defender Joe Rodon.
BBC15 Sept
Capacity has been overwhelmed by heatwaves that have pushed white goods to breaking point “In Oxfordshire, recycling centres are filling almost three articulated lorries with discarded fridges every week,” says Simon Perry of W&S Waste Management, which runs a recycling centre in Ardley. Together, those fridges would cover an area just under half the size of a football pitch. But the space to store them – in Oxfordshire and beyond – has become a growing problem after the Local Government Association (LGA) warned that a mountain of broken fridges was rising in waste centres across England and Wales, as this year’s heatwaves push more white goods to breaking point, and a trend for second/backup refrigeration products keeps growing. Continue reading...
The Guardian•Sarah Marsh Consumer affairs correspondent15 Sept
In today’s newsletter: Plaid Cymru, the SNP and Sinn Féin have signed an agreement for greater powers, as pressure grows on Westminster over the UK’s future Good morning. Back in May, the shape of British politics shifted dramatically. I’ll forgive you if you were too preoccupied refreshing Andrew Sparrow’s live blog for the latest speculation about Keir Starmer to notice, but since 7 May, centre-left nationalist parties that ultimately aspire to leave the UK have been in government for the first time simultaneously in Scotland, Wales and Northern Ireland. This week sees the initial codification of that shift. In Cardiff yesterday, Plaid Cymru leader Rhun ap Iorwerth, Scottish National party leader John Swinney and Sinn Féin vice-president Michelle O’Neill (who shares power with the Democratic Unionist party) affirmed their countries’ right to seek independence from the UK. Along with the leader of the opposition in Ireland, Mary Lou McDonald, they signed a memorandum of understanding that called on Westminster “to prepare, plan and facilitate constitutional change in Wales, Scotland and Northern Ireland”. And they posed for a fair number of group photos too. Reform UK | Andy Burnham’s government could thwart Reform’s unprecedented £72m donations with retrospective restrictions on political donors that will include tough new residency requirements, ministers have announced. AI | Donald Trump has dismissed calls to increase controls on AI as a “sick conspiracy”, as stocks linked to the technology slumped after appeals from Anthropic, OpenAI and SpaceX leaders on the weekend for the industry to slow down. Nato | Nato fighter jets shot down a drone over Lithuania after an alert was issued in the capital and surrounding region, while Poland scrambled fighter jets less than a day after retrieving a suspected Russian drone adrift in its waters. Middle East | Yemen’s Houthi rebels have seized two strategic islands in the Red Sea, reinforcing the Iran-backed group’s ability to control a key shipping route, as concerns mount that the world is facing a new oil supply crisis. Lucy Letby | Two leading experts have quit Lucy Letby’s defence team over concerns about the “scientific credibility” of some of its evidence. Continue reading...
The Guardian•Libby Brooks15 Sept