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Cancer-linked protein binds to chromosome in unexpected way, study finds

A new 3D structure of a cancer-linked protein bound to its cellular partner reveals details of how the protein binds to chromosomes and could offer insights for future disease treatments. The protein—BRD4—plays a critical role in how cells read, copy and repair DNA and helps determine how different kinds of cells are made; it has been linked to many types of cancer and is considered a promising target for future therapies. The study, led by scientists at Penn State and published in the journal Molecular Cell, found that BRD4 can attach to DNA-packaging structures in cells even without a molecular signal long believed to be necessary for the interaction.

Phys.orgPhys.org14 Sept

Rivers may be carrying more microplastics into the world's oceans than previously thought

Microplastics are a modern environmental menace and a potential threat to human health. These tiny pieces of plastic, measuring from 1 to 5,000 micrometers, come mainly from larger plastics as well as sources such as paints and cosmetics. They are found in almost every corner of the planet, and a new study published in Science suggests rivers may be carrying far more of them into the ocean than previously thought.

Phys.orgPhys.org14 Sept

Series of reactions reveals how complex carbon chemistry can begin in frigid space

Before there was Earth, there was chemistry. In the unimaginable cold, dark clouds where stars and planets are born, carbon molecules assemble into more complex forms—starting a chemical journey that could eventually deliver some of life's basic ingredients to young planets. There's only one problem: These molecules need heat to form. At least that's what scientists have long believed. But new research from FIU chemist Alexander Mebel reveals such chemistry can actually happen at temperatures nearing absolute zero, which is -460°F (-273°C).

Phys.orgPhys.org14 Sept

Novel solvent recipe boosts efficiency of organic solar cells

In a study recently published in the Chemical Engineering Journal, a research team from National Taiwan University and international collaborators have developed a straightforward solvent-mixing strategy to significantly boost the performance of next-generation all-polymer organic solar cells. By adding a small fraction of a cosolvent during fabrication, the team successfully resolved a long-standing challenge in controlling film quality, opening new possibilities for commercializing flexible, efficient and sustainable clean energy technology.

Phys.orgPhys.org14 Sept